Abstract: The iQUEST Project is funded by the National Science Foundation to infuse the use of innovative technology in middle school classrooms to support teachers and students becoming 21st century workforce. The professional development model builds teacher confidence, skills, and knowledge while provided rich resources and support for the integration of technology and application of appropriate teaching strategies to engage students in learning science. Student interests and attitudes toward science increase as they participate in technology rich learning experiences developed by teams of teachers through collaborative lesson study investigations. Project classrooms are connected with scientists and experts through videoconferencing, online collaboration and field trips to research labs and partner facilities. The project has documented the lessons and implementation process through classroom observations and surveys.